WNTsignalingpathway相关论文
Protective effect of Pai-Nong-San against AOM/DSS-induced CAC in mice through inhibiting the Wnt sig
Pai-Nong-San (PNS),a prescription of traditional Chinese medicine,has been used for years to treat abscessation-in-duced......
Liver fibrosis is a life-threatening disease, with challenging morbidity and mortality for healthcare systems worldwide.......
Suppression of Sclerostin alleviates radiation-induced bone loss by protecting bone forming cells an
Aim Radiation damage to the skeleton within the radiation field results in a spectrum of bone changes from mild osteopen......
Ephb4 Promotes Osteogenesis of CTLA4 Modified Bone Marrow Derived Mesenchymal Stem Cells Through Cro
Background: Cytotoxic T lymphocyte–associated antigen 4-Ig (CTLA4-Ig) modified bone marrow derived mesenchymal stem cel......
Metastasis-related miR-30c/e suppresses cancer stemness by targeting LRP6in hepatocellular carcinoma
目的 Hepatocellular carcinoma(HCC)is an aggressive cancer with a dismal outcome largely due to metastasis and postsurgic......
Cerebrospinal Fluid Pulsation Likely Promotes the Osteogenesis and Remodeling of de novo Laminae via
Objective: The objective of this study is the effect of cerebrospinal fluid pulsation (CSFP) on the osteogenesis and rem......
Cerebrospinal Fluid Pulsation Likely Promotes the Osteogenesis and Remodeling of de novo Laminae via
In this study, we determined the effect of cerebrospinal fluid pulsation (CSFP) on the osteogenesis and remodeling of de......
Nek2B activates the wnt pathway and promotes triplenegative breast cancer chemotherapy-resistance by
Objective The molecular mechanism of chemotherapy-resistance in triple-negative breast cancer(TNBC)is unclear.Centrosoma......
Objective To understand the regulation of NNK on the transcriptional expression of DKK3 in cervical cancer-associated fi......
The canonical Wnt/β-catenin pathway plays an important role in hair cycle induction.Wnt5a is a non-canonical Wnt family......
Objective:With peoples changing life style and dietary habit,the prevalence of type 2 diabetes mellitus(T2DM)has become ......
DACT2 is Frequently Methylated in Human Gastric Cancer and Methylation of DACT2 Activated Wnt Signal
Dapper, Dishevelled-associated antagonist of β-catenin (DACT), is a key regulator of the Wnt signaling pathway.The purp......
Ischemic brain injury is the leading cause of cerebrovascular disease, which is one of the three diseases of highest inc......
Epigenetic regulation of Wnt signaling pathway gene SRY-related HMG-box 17 in papillary thyroid carc
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Danzhi Jiangtang capsule(丹蛭降糖胶囊)alleviate hyperglycemia and periodontitis via Wnt/β-catenin signalin
OBJECTIVE:To elucidate whether Danzhi Jiang-tang capsule(丹蛭降糖胶囊,DJC) has treatment ef-fects on diabetic periodonti......
目的探讨慢性肾衰竭（chronic renal failure，CRF）幼鼠胫骨生长板软骨细胞初级纤毛高表达加速软骨细胞分化的机制。方法选取雄性4周龄S......
骨关节炎是以关节软骨的破坏、骨赘形成及关节间隙变窄为特征的慢性退变性关节疾病，严重影响患者的生活质量，然而其发病机制目前仍不......
作为T-box基因家族中的一员,Tbx3基因在胚胎发育过程中具有重要的作用.Tbx3基因通过一些信号通路来调控胚胎的发育,如Tbx3能够通过......
Wnt信号传导通路在胚胎发育及生命体成长过程中起关键调控作用,参与维持诸多组织及器官的正常生理功能.多种疾病的发生和发展过程......
OBJECTIVE:To investigate the therapeutic effects of Jiazhu decoction (JZD) in combination with cyclophosphamide (CTX) on......
目的探讨Wnt受体信号通路与早产儿视网膜病(ROP)的关系。方法选择2011年1月至2015年6月我院新生儿重症监护病房诊断严重ROP的早产......
阿尔茨海默病(Alzheimers disease,AD)是一种中枢神经系统的退行性变性疾病,主要表现为进行性的认知功能障碍和精神神经异常.AD的......
Wnt信号通过复杂的信号传导通路在血液肿瘤的发生发展中起重要的调节作用，Wnt信号抑制因子的基因启动子区域的异常甲基化导致其功能......
Wnt信号通路在骨骼发育中扮演重要角色,并通过多种途径影响骨肉瘤(OS)细胞株的增殖、凋亡和浸润转移.近年来,wnt信号通路在OS细胞......
目的：探讨经典Wnt信号通路在孤独症发病中的作用。方法：利用丙戊酸孤独症大鼠模型，检测经典Wnt信号通路信号分子在孤独症大鼠前额叶皮......
